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. 2016 Jul 7;11(7):e0158887. doi: 10.1371/journal.pone.0158887

Table 3. Clinical data, and diffusion and perfusion parameters in contrast-enhancing and non-enhancing regions according to survivala.

Characteristic Survival < 6 months (n = 8) Survival > 6 months (n = 7) p-value
Male/Female 37.5% /62.5% 57.1% /42.9% 0.447
Age 68.5 (63.75–72.5) 69 (59.5–75) 1.00
Motor deficit (%) 50 42.9 0.782
Language deficit (%) 50 14.3 0.143
Karnofsky Performance Score 90 (80–100) 90 (85–95) 0.903
CER (mL) 16.05 (12.28–19.67) 13.82 (8.48–23.78) 0.779
Necrosis (mL) 5.47 (2.95–10.18) 4.11 (2.15–7.05) 0.397
NCER (mL) 49.66 (34.43–70.23) 33.99 (26.01–58.11) 0.281
fCER (%) 11.43 (10.64–14.53) 9.13 (7.63–10.41) 0.009
DCER (x10-3mm2/s) 0.997 (0.904–1.056) 1.115 (1.040–1.260) 0.121
D*CER (x10-3mm2/s) 26.448 (24.774–30.702) 20.507 (18.254–23.601) 0.021
ADCCER(x10-3mm2/s) 100.39 (88.9–113.83) 123.51 (106.48–131.59) 0.072
rCBFCER (ml/100g/min) 67 (47.12–78.48) 46.15 (28.24–49.87) 0.04
rCBVCER (ml/100g) 5.57 (4.67–6.51) 3.87 (2.95–4.55) 0.04
max rCBFCER (ml/100g/min) 165.9 (156.2–173.4) 140.5 (133.2–147.7) 0.07
max rCBVCER (ml/100g) 14.1 (11.0–16.8) 10.6 (9.9–11.5) 0.04
fNCER (%) 2.27 (1.18–3.11) 2 (1.94–3.15) 0.602
DNCER (x10-3mm2/s) 1.381 (1.267–1.662) 1.486 (1.305–1.787) 0.779
D*NCER (x10-3mm2/s) 6.352 (3.752–7.204) 3.764 (2.523–4.264) 0.094
rCBFNCER (ml/100g/min) 23.69 (13.37–33.67) 22.92 (17.39–23.68) 0.779
rCBVNCER (ml/100g) 1.06 (0.85–1.43) 1.75 (1.31–1.86) 0.336
Treatment 0.067
Standard (n) 1 4
Non-standard (n) 7 3
Survival (months) 4 (2–5.25) 8.5 (7–10) 0.001

a Significant p-values are highlighted.