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. 2016 Jul 7;12(7):e1006127. doi: 10.1371/journal.pgen.1006127

Fig 5. Association of SNP rs4773144 with collagen IV level in atherosclerotic plaques and plaque cap thickness.

Fig 5

Atherosclerotic coronary arteries from different individuals were genotyped for SNP rs4773144 and subjected to histopathological analyses using Image-Pro software. (A) A representative image of immunostaining, blue color indicates COL4A2 staining, and brown smooth muscle alpha-actin. ×400 original magnification. (B) Percentages of COL4A2 immunostain positive areas in atherosclerotic plaques in different genotype groups. (C) Atherosclerotic plaque cap thickness in different genotype groups. (D) Atherosclerotic plaque cap/intima ratios in different genotype groups. Columns and error bars in B-D are mean and SEM values; p-values shown are for an additive genetic model.