Fig. 1.

Representative images of Zif268 (A–D) and cytochrome oxidase (E) staining in coronal brain slices. Dashed lines denote the extent of the regions of interest based on Wyss & Van Groen (1992). A, C show examples of anti-Zif268 staining in the retrosplenial cortex and the dorsal hippocampus in a sham brain while B, D display the same regions in a lesioned brain. E – an example of cytochrome oxidase staining comprising both the retrosplenial and the hippocampal regions. Note that the normalization ROI extends beyond the border of the photograph. DG, dentate gyrus; Rga, retrosplenial granular a cortex; Rgb, retrosplenial granular b cortex; Rdg, retrosplenial dysgranular cortex; ROI, region of interest. Scale bar = 1 mm.