Fig. 1.
Chlamydia trachomatis induces PKR activation in mDC. (A) Western blot of PKR phosphorylation following stimulation with indicated PRR agonists for 4 h. Panel below indicates quantification by densitometry of the phosphorylated PKR band. (B) Western blot of PKR phosphorylation (pPKR) following infection with C. trachomatis for 8 h at different multiplicities of infection (MOI). (C) Western blot of PKR phosphorylation (pPKR) following stimulation with live C. trachomatis (CT), gamma ray-attenuated C. trachomatis (γ-CT), heat-treated C. trachomatis, LPS or heat-treated LPS for 8 h. Right panel indicates by densitometry of the phosphorylated PKR band.