Fig. 3.
PKR activation is independent of NADPH oxidase. (A) Western blot of PKR phosphorylation (pPKR) in wild type (cybb+/+) or NADPH oxidase-deficient (cybb−/−) BMDM following infection with C. trachomatis for 8 h. Panel on the right indicates quantification by densitometry of the phosphorylated PKR band. (B) Western blot of PKR (pPKR) phosphorylation in mDC from a healthy donor or a CGD donor following infection with C. trachomatis for 6 h. Panel on the right indicates quantification by densitometry of the phosphorylated PKR band.