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. Author manuscript; available in PMC: 2016 Jul 7.
Published in final edited form as: Int J Sci Basic Appl Res. 2016;26(1):26–46.

Figure 4.

Figure 4

Mitochondrial DNA damage (A) Relative amplification of mtDNA and (B) Poisson analysis for detection of lesions frequency in mtDNA both of liver and brain tissues of mice. Bars represent mean ±1.96 (SD) with distribution of samples per group in scatter blot column. (A) Relative amplification for liver tissue-Interval of confidence at 95% were as follow: Control: 1+/−1.96(0), NAC: 0.92 +/− 1.96 (0.10), PQ: 0.71 +/− 1.96 (0.07), and PQ+NAC: 0.90 +/− 1.96 (0.09). The sample size of the experimental groups was as follow: Control (N=5), NAC (N=5), PQ (N=4), and PQ+NAC (N=5). Relative amplification for brain tissue-Interval of confidence at 95% were as follow: Control: 1+/−1.96(0), NAC: 0.95 +/− 1.96 (0.18), PQ: 0.63 +/− 1.96 (0.16), and PQ+NAC: 0.69 +/− 1.96 (0.15). The sample size of the experimental groups was as follow: Control (N=5), NAC (N=4), PQ (N=5), and PQ+NAC (N=5). (B) Poisson analysis for liver tissue-Interval of confidence at 95% were as follow: NAC: 0.07 +/− 1.96 (0.10), PQ: 0.33 +/− 1.96 (0.08), and PQ+NAC: 0.07 +/− 1.96 (0.10). The sample size of the experimental groups was as follow: NAC (N=5), PQ (N=4), and PQ+NAC (N=5). Poisson analysis for brain tissue-Interval of confidence at 95% were as follow: NAC: 0.11 +/− 1.96 (0.14), PQ: 0.47 +/− 1.96 (0.20), and PQ+NAC: 0.30 +/− 1.96 (0.16). The sample size of the experimental groups was as follow: NAC (N=4), PQ (N=5), and PQ+NAC (N=4).