TABLE 2.
Seizure description, treatment, and brain imaging
| Subject | Status epilepticus | Any seizures with clinical correlates | Seizure description | Antiseizure medications administered | Imaging |
|---|---|---|---|---|---|
| 1 | Yes | Yes | 25 focal R central seizures lasting 0.5–3.5 min | PB | Brain MRI Bilateral deep and periventricular foci of PVL |
| 2 | Yes | No | 29 bi-occipital seizures lasting 2–30 min | PB | Brain MRI Bilateral deep and periventricular foci of hemorrhagic PVL |
| 3 | Yes | No | >100 bi-central and vertex seizures lasting 0.5–3 min | LEV, PB | Head US Bilateral IVH, periventricular hemorrhage vs hemorrhagic infarct |
| 4 | No | No | 1 R central and 1 L occipital seizure lasting 1 min | None | Brain MRI Small SDH along flax and tentorium, small intraparenchymal hemorrhage in R cerebellar hemisphere and R posterior parietal lobe |
| 5 | No | No | 5 L central seizures lasting 0.25–1 min | PB | Brain MRI L post frontal and anterior parietal infarction, R frontal lobe infarction |
| 6 | Yes | No | 13 R central seizures lasting 1–3 min | PB, LEV | Head US 2 large intraparenchymal lesions in L hemisphere suggestive of ICH |
| 7 | No | No | 9 L occipital 1-seizures lasting 5 min | PB | Brain MRI Cystic PVL central semiovale and corona radiate bilaterally |
| 8 | Yes | No | 5 bi-occipital seizures lasting 2–13 min | PB | Brain MRI PVL L parietal white matter region, L tentorial SDH, bilateral cerebral microhemorrhages |
| 9 | Yes | No | 34 L occipital seizures lasting 2–4 min | LEV | Brain MRI PVL corpus callosum, periventricular deep white matter, microhemorrhages R frontal and parietal deep white matter, R lateral medulla and cerebellar peduncle, SDH posterior flax and tentorium |
| 10 | Yes | No | >100 R frontal-central-temporal temporal seizures lasting 0.25–1.5 min | PB, LEV | Brain MRI Subacute infarctions in the R frontal lobe and L frontal lobe |
| 11 | No | No | 3 L occipital seizures lasting 1–20 min | PB, LEV | Head US Increased echogenicity bilateral thalami, bilateral SDH |
| 12 | Yes | Yes | ~10 seizures per hour for 3 d from multifocal locations lasting 0.5–5 min | PB, LEV | Head US Large area of increased parenchymal echogenicity in the L parietal-occipital region, compatible with hemorrhagic infarction, IVH left greater than right |
| 13 | No | No | 8 diffuse seizures lasting 0.1–2 min | PB | Head US Evolving left caudothalamic groove germinal matrix hemorrhage with intraventricular synechia |
PB, Phenobarbital; MRI, magnetic resonance imaging; PVL, periventricular leukomalacia; LEV, levetiracetam; US, ultrasound; IVH, intraventricular hemorrhage; SDH, subdural hematoma; R, right; ICH, intracranial hemorrhage.