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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Neurochem. 2016 May 16;138(2):328–338. doi: 10.1111/jnc.13639

Figure 4.

Figure 4

Elevation of TRPA1 mRNA level 1 week after spinal cord injury and its suppression by phenelzine. Spinal dorsal horn (1 cm long including T10), dorsal root ganglia (DRG, L1–L6), and paw skin were assessed 7 days after SCI. Specifically, the TRPA1 mRNA levels were significantly increased in dorsal horn, DRG, and paw skin following SCI (P < 0.05 in dorsal horn and DRG, and P < 0.001 in paw skin group when compared to sham). However, this elevated TRPA1 mRNA was significantly attenuated in all three tissue types with the continuous daily IP injection of phenelzine (15 mg/kg) for a week commencing immediately following trauma. (* P<0.05, ≠ P<0.005 when compared to SCI only, One-way ANOVA and Tukey test). N=5–6 in each group. All values were expressed as mean ±SEM.