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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Neurochem. 2016 May 16;138(2):328–338. doi: 10.1111/jnc.13639

Figure 6.

Figure 6

Post-SCI elevation of urine 3-HPMA and its suppression by phenelzine and hydralazine. 3-HPMA, an acrolein metabolite, was significantly elevated in urine one day after SCI in rats (3.6 ± 0.31 μg/mg), when compared to sham injured group (2.0 ± 0.25 μg/mg). Both hydralazine and phenelzine treatments resulted in dose dependent reduction in 3-HPMA levels after SCI. Rat urine samples were collected one day after SCI to determine 3-HPMA level. On average, the volume of urine could be collected in a period of 3–4 hours is 1–2 mL. N=5~6 in each group. One-way ANOVA and Tukey test were used for statistical analysis. Significance are indicated in the graph. All values were expressed as mean ± SEM.