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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: J Neurochem. 2016 May 16;138(2):328–338. doi: 10.1111/jnc.13639

Figure 8.

Figure 8

Acute systemic application of phenelzine improved locomotor function recovery after spinal cord injury. Locomotor function was assessed based on Basso, Beattie and Bresnahan (BBB) score in sham-injury, SCI only, and SCI treated with phenelzine. A significant reduction in BBB score was observed in the SCI only group compared to sham injury. Following spinal cord contusion in the SCI + phenelzine group, phenelzine (15 mg/kg) was applied daily through intraperitoneal (IP) injection for 2 weeks immediately following injury. Such treatment significantly improved the BBB score at one, three, and four weeks post-SCI, when compared to the SCI group. One-way ANOVA and Tukey test were used. (≠ P < 0.001 when compared to sham-injured; * P < 0.05 and *** P < 0.001 when compared to injury only. N = 5 in all conditions. All values were expressed as mean ± SEM.