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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Mol Cancer Ther. 2016 May 20;15(7):1691–1701. doi: 10.1158/1535-7163.MCT-16-0032

Figure 5. CDK11 knockdown enhances the cytotoxic effect of paclitaxel in SKOV-3 and OVCAR-8 cell lines.

Figure 5

A: The 5 nM non-lethal dose of CDK11 siRNA was chosen for SKOV-3 and OVCAR-8, and 3 nM and 1 nM doses of paclitaxel for SKOV-3 and OVCAR-8, respectively. Proliferation was assessed by MTT as described in the Materials and Methods. The data represent the mean ± SD of two experiments carried out in triplicate. B: The CDK11 expression SKOV-3 and OVCAR-8 was analyzed by Western blotting with specific antibody to CDK11 and β-actin after transfection with CDK11 siRNA or non-specific siRNA.