Table 2.

Genome-wide significant loci in the NSS1, NSS2 and PPDS individual analyses and meta-analyses from the standard GWAS analysis

Chr.	Position	SNP	Nearest gene	A1	A2	Population	Study	FRQ	INFO	P-value	OR
5	55507046	rs159572	ANKRD55	A	C	European A.	NSS1	0.75	1.00	0.9327	1.00
							NSS2	0.73	0.98	0.04543	0.84
							NSS-meta			0.2337	0.94
							PPDS	0.73	1.00	0.3608	0.94
							All-meta			0.1334	0.94
5	55507046	rs159572	ANKRD55	A	C	African A.	NSS1	0.46	1.04	4.91×10−6	1.57
							NSS2	0.44	0.95	1.16×10−3	1.74
							NSS-meta			2.34×10−8	1.62
							PPDS	0.47	1.03	0.284	1.18
							All-meta			6.13 ×10−8	1.51
5	55507046	rs159572	ANKRD55	A	C	Latino A.	NSS1	0.68	1.03	0.5213	1.07
							NSS2	0.67	0.96	0.2131	0.82
							NSS-meta			0.8814	0.99
							PPDS	0.69	1.09	0.07136	0.81
							All-meta			0.2281	0.92
Chr.	Position	SNP	Nearest gene	A1	A2	Population	Study	FRQ	INFO	P-value	OR
19	20906220	rs11085374	ZNF626	A	T	European A.	NSS1	0.32	0.98	3.67×10−6	0.77
							NSS2	0.30	0.81	3.62×10−3	0.77
							NSS-meta			4.59×10−8	0.77
							PPDS	0.31	0.97	0.496	1.05
							All-meta			5.40×10−5	0.86
19	20906220	rs11085374	ZNF626	A	T	African A.	NSS1	0.51	0.90	0.6318	0.95
							NSS2	0.50	0.67	0.6213	1.10
							NSS-meta			0.8513	0.98
							PPDS	0.51	0.85	0.7949	0.96
							All-meta			0.7733	0.98
19	20906220	rs11085374	ZNF626	A	T	Latino A.	NSS1	0.27	0.92	0.0799	1.23
							NSS2	0.25	0.76	0.6498	1.09
							NSS-meta			0.08197	1.19
							PPDS	0.26	0.93	0.342	0.87
							All-meta			0.3765	1.08

^*A1: risk allele; A2: non-risk allele; FRQ: overall risk allele frequency; INFO: imputation quality score; OR: odds ratio; NSS-meta: meta-analysis between NSS1 and NSS2 results; All-meta: meta-analysis between NSS1, NSS2 and PPDS results

^**Position is in NCBI Build 37/UCSC hg19 coordinates.