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CCI induces neuroinflammation in Cdk5 cKO mice. (a and b) Neuroinflammation indicated by increased astrocyte activation in the ipsilateral hippocampal area of the dentate gyrus (DG) (a), as compared to the contralateral DG (b) using GFAP immunostaining. (c and d) Increased number of reactive microglia in the ipsilateral hippocampal CA3 region (c), as compared to contralateral CA3 (d) using Iba1 immunostaining. Scale bars: 100 μm.
