Table 4.
p27 expression in SBNETs and PNETs with somatic mutationsa
| Mutation | Tissue | H-score | Location of expression |
|---|---|---|---|
| Frameshift (SBNET 243-1) | SBNET primary | 11 | Nucleus |
| SBNET primary | 66 | Cytoplasm | |
| LN metastasis | 10 | Nucleus | |
| LN metastasis | 225 | Cytoplasm | |
| Frameshift (SBNET 308-1) | SBNET primary | 12 | Nucleus |
| SBNET primary | 67 | Cytoplasm | |
| Frameshift (SBNET 318-1) | SBNET primary | 0 | Nucleus |
| SBNET primary | 0 | Cytoplasm | |
| LN metastasis | 0 | Nucleus | |
| LN metastasis | 0 | Cytoplasm | |
| Liver metastasis | 0 | Nucleus | |
| Liver metastasis | 0 | Cytoplasm | |
| Missense (SBNET 162-1) | SBNET primary | 30 | Nucleus |
| SBNET primary | 220 | Cytoplasm | |
| Missense (PNET 224-1) | PNET primary | 225 | Nucleus |
| PNET primary | 27 | Cytoplasm | |
| LN metastasis | 210 | Nucleus | |
| LN metastasis | 100 | Cytoplasm |
a
Each sample was assessed for the presence of p27 expression, which is quantified by the H-score. Cellular location of expression was also noted.