Table 1.

Collagen binding peptides and their applications.

Collagen binding peptides	Source	Target	Kd (μM)*	Application	Ref.
RRANAALKAGELYKSILYGC	Collagen I platelet receptor	Collagen type I	0.86	Modulate collagen fibrillogenesis and inhibit MMP-mediated collagen degradation	7,8
MIVIELGTNPLKSSGIENGAF QGMKK	Leucine-rich repeats (LRR) 4–5 of Decorin	Collagen type I	0.394	Induce collagen mineralization in bone defects	16
LRELHLNNN	Inner surface of LRR 10 of Decorin	Collagen type I	0.17	Promote controlled release of molecules ≥2 KDa	18
WREPSFCALS	Von Willebrand Factor	Collagen type I	100	Promote vascularization and cellularization	20,21
TKKTLRT	Collagenase	Collagen type I	≤100	Promote vascularization and cellularization	21
WYRGRL	Phage display	Collagen type II	n.d.	Target articular cartilage	23–25
KLWVLPK	Phage display	Collagen type IV	n.d.	Target sites exposed collagen in blood vessels damaged by balloon angioplasty	27

^*n.d. = not determined