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Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease logoLink to Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
. 2016 May 26;5(6):e002056. doi: 10.1161/JAHA.116.002056

Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease

PMCID: PMC4937239  PMID: 27231020

Correction

In the article by Douvris et al, “Functional Analysis of the TRIB1 Associated Locus Linked to Plasma Triglycerides and Coronary Artery Disease,” which published online June 3, 2014, and appeared in the June 2014 issue of the journal (J Am Heart Assoc. 2014;3:e000884 doi: 10.1161/JAHA.114.000884), the legend to Figure 2 contained several errors. On page 7, in the third and fourth lines of the legend to Figure 2, “(AA, n=38 5)” has been corrected to “(BB, n=385)” and “homozygous risk (BB, n=346)” has been corrected to “homozygous reference (AA, n=346).” In the fifth and sixth lines, “AA vs BB (P=0.0036) and AB vs BB (P=0.0044)” has been corrected to “AA vs AB (P=0.0036) and AA vs AB (P=0.0044).” The corrected figure and legend are presented below.

Figure 2.

Figure 2

Risk SNP at rs2001844 is associated with higher TG and lower HDL levels. A, Fasting levels of HDL and TG (normalized) in non‐CAD patients with homozygous risk (BB, n=385), heterozygous (AB, n=666) and homozygous reference (AA, n=346) genotypes. Error bars represent 95% C.I. For HDL, statistically significant differences were observed for AA vs BB (P=0.0036) and AA vs AB (P=0.0044) only. For TG, all groups were statistically different (P<0.05). B, Levels of TRIB1 transcript were measured in a total of 160 patients. (50 AA , 56 AB, 54 BB) well matched for sex, age and BMI. Data are normalized to PPIA for each patient and bars represent the means±95% CI. TRIB1 mRNA levels were statistically significant between AA and BB only (P=0.008). BMI indicates body mass index; CAD, coronary artery disease; HDL, high‐density lipoprotein; SNP, single nucleotide polymorphism; TG, triglycerides.

The authors regret these errors.

The online version of the article has been updated and is available at http://jaha.ahajournals.org/content/3/3/e000884.

J Am Heart Assoc. 2016;5:e002056 doi: 10.1161/JAHA.116.002056


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