Table 2.
Distribution of Serum Inflammatory Markers Among the Multicenter AIDS Cohort Study (MACS) Participants Who Had Cardiac CT Scana
| HIV Infected (N=575) | HIV Uninfected (N=348) | SD | P Value | |
|---|---|---|---|---|
| Interleukin‐6, pg/mL | 1.5 (1.0–2.5) | 1.3 (0.9–2.1) | 6.1 | 0.001b |
| ICAM‐1, ng/mL | 257.8 (214.7–315.0) | 228.6 (193.1–273.5) | 116.2 | 0.007b |
| Fibrinogen, mg/dL | 326 (278–377) | 332 (292–376) | 92.7 | 0.63 |
| D‐dimer, μg/mL | 0.17 (0.11–0.29) | 0.20 (0.13–0.3) | 0.8 | 0.43 |
| CRP, mg/dL | 1.24 (0.64–2.76) | 0.95 (0.52–1.92) | 4.2 | <0.001b |
| sTNFαR I, pg/mL | 1178 (973–1495) | 1160 (953–1378) | 1154 | 0.002b |
| sTNFαR II, pg/mL | 6622 (5390–8285) | 5844 (4961–6902) | 3519 | <0.001b |
CPR indicates C‐reactive protein; ICAM‐1, intracellular adhesion molecule 1; sTNFαR, soluble‐tumor necrosis.
a
Inflammatory markers are presented as median (interquartile range). P values are calculated using t test after log transformation in all the markers except fibrinogen. SDs are provided to facilitate interpretation of standardized variables.
b
Statistically significant findings.