Table 2. PM group p-values indicating the strength of correlation between step length variability and molecular parameters using regression method estimated by generalised estimating equations.

	Step length variability DTC Finger tapping			Step length variability DTC Counting by 3			Step length variability DTC Counting by 7
	b	s.e	p-value	b	s.e	p-value	b	s.e	p-value
FMR1/3IC	−0.139	0.077	0.070	−0.104	0.125	0.407	0.074	0.081	0.362
FMR1/2IC	0.044	0.082	0.590	0.050	0.155	0.749	0.154	0.111	0.166
FMR1/GUS	−0.164	0.057	0.004	−0.251	0.130	0.054	−0.005	0.099	0.959
GUS/2IC	0.536	0.126	0.00002	0.677	0.246	0.006	0.451	0.113	0.00007
SDHA/EIF4A2	0.139	0.158	0.377	0.062	0.199	0.756	0.139	0.170	0.415
AR	−0.033	0.168	0.843	−0.226	0.181	0.212	−0.193	0.169	0.252
FMR1/3IC /AR	−0.009	0.116	0.935	0.140	0.158	0.378	0.177	0.107	0.100
FMR1/2IC /AR	0.252	0.141	0.074	0.529	0.156	0.001	0.416	0.128	0.001
GUS/2IC/AR	0.396	0.141	0.005	0.427	0.124	0.001	0.325	0.144	0.024
SDHA/EIF4A2/AR	0.066	0.175	0.704	0.100	0.230	0.665	0.136	0.196	0.489

Note: b = standardised regression coefficient. Significant values in bold.

AR = FMR1 activation ratio; DTC = Dual Task Cost; EIF4A2 = Eukaryotic initiation factor 4A-2 mRNA; SDHA = succinate dehydrogenase complex, subunit A, flavoprotein (Fp) mRNA. The FMR1 mRNA levels were normalized to: (i) GUS alone (FMR1/GUS); (ii) mean of EIF4A2, and SDHA mRNA levels (FMR1/2IC); (iii) mean of GUS, EIF4A2, and SDHA mRNA levels (FMR1/3IC); (iv) mean of EIF4A2, and SDHA mRNA levels divided by AR (FMR1/2IC/AR); (v) mean of GUS, EIF4A2, and SDHA mRNA levels divided by AR (FMR1/3IC/AR). The GUS mRNA levels were normalized to: (i) mean of EIF4A2, and SDHA mRNA levels (GUS/2IC); (ii) mean of EIF4A2, and SDHA mRNA levels divided by AR (FMR1/2IC/AR). Other outputs included AR used alone, and EIF4A2 mRNA normalized to SDHA mRNA levels (EIF4A2/SDHA).