Figure 1.
Structure of S. cerevisiae replicator. The general structure of budding yeast replicators and the surrounding nucleosomes is illustrated. Although the precise nucleosome positions vary, the key elements of the replicator are located within a nucleosome-free region with the ORC binding site located asymmetrically within this region. The ORC-ACS consensus sequence shown is derived from Eaton et al. 2010.