Table 2. Genes previously identified to interact with hdac4 that also interact genetically with HDAC4 in Drosophila.
Gene name | Annotation symbol | VDRC/BDSC no. | Method | Molecular function |
---|---|---|---|---|
Gcn5 (PCAF) | CG4107 | VDRC 21786 | RNAi | H4 histone acetyltransferase activity; chromatin binding; H3 histone acetyltransferase activity; histone acetyltransferase activity. |
Cyclic-AMP response element binding protein B | CG6103 | VDRC 101512 BDSC 29332 | RNAi RNAi | DNA binding; sequence-specific DNA binding transcription factor activity; protein dimerization activity; sequence-specific DNA binding. |
Myocyte enhancer factor 2 | CG1429 | VDRC 15550 In house | RNAi Dom neg | Metalloendopeptidase activity; DNA binding; RNA polymerase II distal enhancer or core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; sequence-specific DNA binding transcription factor activity; protein dimerization activity; enhancer sequence-specific DNA binding. |
14-3-3ζ (leo) | CG17870 | VDRC 104496 | RNAi | Protein binding; protein domain specific binding; protein kinase C inhibitor activity; protein homodimerization activity; protein heterodimerization activity; tryptophan hydroxylase activator activity. |
Smrter | CG4013 | VDRC 106701 | RNAi | DNA binding; chromatin binding; transcription corepressor activity; protein binding. |
Lesswright (Ubc9) | CG3018 | VDRC 33685 BDSC 9318 | RNAi Dom neg | SUMO transferase activity; SUMO ligase activity; transcription factor binding; heat shock protein binding; ubiquitin activating enzyme binding. |
Nup358 (RanBP2) | CG11856 | VDRC 38583 | RNAi | Zinc ion binding; Ran GTPase binding. |
Sin3A | CG8815 | VDRC 105852 | RNAi | Sequence-specific DNA binding transcription factor activity; transcription cofactor activity; protein heterodimerization activity; chromatin binding. |
CG, computed gene name; VDRC/BDSC no., catalogue number from the Vienna Drosophila Resource Center or the Bloomington Drosophila Stock Center; dom neg, dominant negative.