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. 2016 May 9;203(3):1381–1399. doi: 10.1534/genetics.115.184820

Figure 5.

Figure 5

Comparison of recombination maps inferred using different lookup tables. We simulated n=20 haplotypes under the three-epoch model (6) and using the recombination map shown as a black dashed line. (A) Inferred map ρ^exact obtained using the exact likelihoods for the true demography. (B) Inferred map ρ^miss obtained using the empirically estimated demography in (8). (C) Inferred map ρ^approx obtained using an approximate lookup table for the true demography. (D) Inferred map ρ^const obtained assuming a constant population size of η1. Note that ρ^const is much noisier than the other estimates, while using an inferred demography or an approximate lookup table results in only a very mild reduction in accuracy compared to using the true sampling probabilities. These ρ^ were produced with LDhelmet; using LDhat led to very similar results.