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. 2016 May 2;203(3):1315–1334. doi: 10.1534/genetics.116.188912

Table 2. Simulation results for a neutral locus surrounded by two loci subject to mutation to deleterious alleles (2Ns = 1, 2Nu = 0.1, 2Nv = 0.01, q* = 0.296, N = 50, x0 = 0.5).

Generation 0.5N Generation 2N
2Ns˜ 2Nt˜ Hrel Ps 2Ns˜ 2Nt˜ Hrel Ps
h = 0.1
C = 0
 0.142 (0.00001) 0.142 (0.00001) 1.0008 (0.0001) 0.9842 (0.00006) 0.294 (0.00003) 0.297 (0.00003) 1.0180 (0.0004) 0.5444 (0.0002)
 0.136a 0.136a 0.9841 (0.00004)b 0.268a 0.268a 0.5375 (0.0002)b
C = 0.1
 0.139 (0.00001) 0.139 (0.00001) 1.0001 (0.0001) 0.9843 (0.00006) 0.272 (0.00003) 0.272 (0.00003) 1.0159 (0.0005) 0.5433 (0.0002)
 0.134a 0.134a 0.248a 0.248a
C = 1
 0.115 (0.00001) 0.115 (0.00001) 1.0007 (0.0001) 0.9843 (0.0006) 0.151 (0.00002) 0.151 (0.00002) 1.0010 (0.0005) 0.5412 (0.0002)
 0.110a 0.110a 0.142a 0.142a
C = 10
 0.037 (0.00001) 0.037 (0.00001) 1.0002 (0.0001) 0.9841 (0.0006) 0.028 (0.00001) 0.028 (0.00001) 1.0000 (0.0005) 0.5372 (0.0002)
 0.036a 0.036a 0.028a 0.028a
h = 0.45
C = 0
 0.018 (0.0001) 0.018 (0.0001) 0.9999 (0.0001) 0.9842 (0.00006) 0.036 (0.00003) 0.036 (0.00003) 0.9952 (0.0005) 0.5352 (0.0002)
 0.016a 0.016a 0.9841 (0.00004)b 0.032a 0.032a 0.5375 (0.0002)b
C = 0.1
 0.018 (0.0001) 0.018 (0.0001) 0.9999 (0.0001) 0.9841 (0.00006) 0.034 (0.00003) 0.034 (0.00003) 0.9961 (0.0005) 0.5356 (0.0002)
 0.016a 0.016a 0.030a 0.030a
C = 1
 0.015 (0.0001) 0.015 (0.0001) 0.9996 (0.0001) 0.9841 (0.0006) 0.019 (0.00002) 0.019 (0.00002) 0.9975 (0.0005) 0.5360 (0.0002)
 0.014a 0.014a 0.018a 0.018a
C = 10
 0.005 (0.0001) 0.005 (0.0001) 0.9999 (0.0001) 0.9842 (0.0006) 0.004 (0.0001) 0.004 (0.0001) 0.9998 (0.0005) 0.5337 (0.0002)
 0.004a 0.004a 0.004a 0.004a

C is the scaled recombination rate between the neutral locus and each selected locus. The selection and mutation parameters are the same for each selected locus. Standard errors for 5 × 106 simulations with two selected loci are in parentheses, following the corresponding means.

a

Single-locus simulation values multiplied by two.

b

Values from neutral simulations.