Table 2. Simulation results for a neutral locus surrounded by two loci subject to mutation to deleterious alleles (2Ns = 1, 2Nu = 0.1, 2Nv = 0.01, q* = 0.296, N = 50, x0 = 0.5).
Generation 0.5N | Generation 2N | ||||||
---|---|---|---|---|---|---|---|
2N | 2N | Hrel | Ps | 2N | 2N | Hrel | Ps |
h = 0.1 | |||||||
C = 0 | |||||||
0.142 (0.00001) | 0.142 (0.00001) | 1.0008 (0.0001) | 0.9842 (0.00006) | 0.294 (0.00003) | 0.297 (0.00003) | 1.0180 (0.0004) | 0.5444 (0.0002) |
0.136a | 0.136a | 0.9841 (0.00004)b | 0.268a | 0.268a | 0.5375 (0.0002)b | ||
C = 0.1 | |||||||
0.139 (0.00001) | 0.139 (0.00001) | 1.0001 (0.0001) | 0.9843 (0.00006) | 0.272 (0.00003) | 0.272 (0.00003) | 1.0159 (0.0005) | 0.5433 (0.0002) |
0.134a | 0.134a | 0.248a | 0.248a | ||||
C = 1 | |||||||
0.115 (0.00001) | 0.115 (0.00001) | 1.0007 (0.0001) | 0.9843 (0.0006) | 0.151 (0.00002) | 0.151 (0.00002) | 1.0010 (0.0005) | 0.5412 (0.0002) |
0.110a | 0.110a | 0.142a | 0.142a | ||||
C = 10 | |||||||
0.037 (0.00001) | 0.037 (0.00001) | 1.0002 (0.0001) | 0.9841 (0.0006) | 0.028 (0.00001) | 0.028 (0.00001) | 1.0000 (0.0005) | 0.5372 (0.0002) |
0.036a | 0.036a | 0.028a | 0.028a | ||||
h = 0.45 | |||||||
C = 0 | |||||||
0.018 (0.0001) | 0.018 (0.0001) | 0.9999 (0.0001) | 0.9842 (0.00006) | 0.036 (0.00003) | 0.036 (0.00003) | 0.9952 (0.0005) | 0.5352 (0.0002) |
0.016a | 0.016a | 0.9841 (0.00004)b | 0.032a | 0.032a | 0.5375 (0.0002)b | ||
C = 0.1 | |||||||
0.018 (0.0001) | 0.018 (0.0001) | 0.9999 (0.0001) | 0.9841 (0.00006) | 0.034 (0.00003) | 0.034 (0.00003) | 0.9961 (0.0005) | 0.5356 (0.0002) |
0.016a | 0.016a | 0.030a | 0.030a | ||||
C = 1 | |||||||
0.015 (0.0001) | 0.015 (0.0001) | 0.9996 (0.0001) | 0.9841 (0.0006) | 0.019 (0.00002) | 0.019 (0.00002) | 0.9975 (0.0005) | 0.5360 (0.0002) |
0.014a | 0.014a | 0.018a | 0.018a | ||||
C = 10 | |||||||
0.005 (0.0001) | 0.005 (0.0001) | 0.9999 (0.0001) | 0.9842 (0.0006) | 0.004 (0.0001) | 0.004 (0.0001) | 0.9998 (0.0005) | 0.5337 (0.0002) |
0.004a | 0.004a | 0.004a | 0.004a |
C is the scaled recombination rate between the neutral locus and each selected locus. The selection and mutation parameters are the same for each selected locus. Standard errors for 5 × 106 simulations with two selected loci are in parentheses, following the corresponding means.
Single-locus simulation values multiplied by two.
Values from neutral simulations.