Fig. 6.

Rat SCI-CSF immunoblotting validation. A, Time course of post-SCI biomarkers release and new candidate marker validation illustrated by Western blot of rat spinal cord CSF samples (sham, and two SCI severity) collected at three time points (4 h, 24 h, and 7 days), the markers probed are alphaII-spectrin, transferrin, GFAP, TPI-1, UCHL-1, and PEA-15, B, Immunoblotting quantification of CSF samples (sham and two SCI severity levels at three time points) for Alpha II-spectrin breakdown products SBDP145 & SBDP120, GFAP and GFAP-BDP (38K), TPI-1, and PEA-15 biomarkers. Mean + S.E. are shown. (* p < 0.05, compared with corresponding sham, unpaired t test).