Fig. 4.

Volcano plots for yeast and human proteins in three comparisons with extracted data of Lib1. Classification based on protein level analysis, FC > 1.5 and pval < 0.05. Purple dots represent true positive (TP) proteins, i.e. yeast proteins detected as differentially expressed; blue represents true negatives (TN), i.e. human proteins not detected as differentially expressed; green represents false positives (FP), i.e. human proteins detected as differentially expressed; and red represent false negatives (FN), i.e. yeast proteins not detected as differentially expressed. The numbers inside the circles show the number of peptides identified for the respective protein.