Table 3.

Hazard ratios of CHD (only MI) from multivariable Cox proportional hazards model

Variable		Women			Men
		HR	95 % CI	P	HR	95 % CI	P
Model 1 (Laboratory based)a
	Age (in 10 yrs)	0.99	0.71–1.38	0.968	1.38	0.97–1.98	0.078
	Total cholesterol (mg/dl in 10 yrs)	0.99	0.88–1.12	0.930	1.13	1.03–1.26	0.015
	HDL cholesterol (mg/dl in 10 yrs)	0.77	0.39–1.53	0.455	0.50	0.26–0.98	0.042
	Systolic blood pressure (mm Hg in 10 yrs)	1.18	0.96–1.55	1.452	1.52	1.23–1.89	0.0001
	History of blood pressure treatment	0.78	0.15–3.99	0.763	1.54	0.45–5.30	0.490
	Current smoker	0.77	0.27–2.23	0.628	1.88	0.93–3.81	0.081
	Diabetes	1.22	0.46–3.26	0.694	1.34	0.61–2.9	0.466
Model 2 (WHO with cholesterol)b
	Age (in 10 yrs)	1.10	0.70–1.73	0.683	1.39	0.87–2.21	0.168
	Total cholesterol (mg/dl in 10 yrs)	0.97	0.87–1.08	0.614	1.01	0.89–1.15	0.878
	Systolic blood pressure (mm Hg in 10 yrs)	1.21	0.91–1.61	0.187	1.62	1.22–2.15	0.0008
	History of blood pressure treatment	0.80	0.16–3.92	0.781	1.80	0.51–6.31	0.357
	Current smoker	0.53	0.11–2.64	0.437	1.54	0.61–3.93	0.363
	Diabetes	1.58	0.47–5.23	0.455	1.37	0.51–3.70	0.534
Model 3 (WHO without cholesterol)c
	Age (in 10 yrs)	1.05	0.67–1.63	0.833	1.45	0.90–2.34	0.123
	Systolic blood pressure (mm Hg in 10 yrs)	1.11	0.76–1.62	0.606	1.77	1.35–2.32	<0.0001
	History of blood pressure treatment	0.44	0.06–3.10	0.412	1.94	0.48–7.82	0.348
	Current smoker	0.52	0.11–2.56	0.421	1.56	0.61–3.98	0.353
	Diabetes	1.44	0.43–4.83	0.556	1.41	0.53–3.78	0.488
Model 4 (Non-laboratory based)d
	Age (in 10 yrs)	0.83	0.51–1.34	0.448	1.36	0.89–2.08	0.149
	Systolic blood pressure (mm Hg in 10 yrs)	1.13	0.86–1.48	0.392	1.57	1.21–2.04	0.0007
	History of blood pressure treatment	1.65	0.36–7.51	0.516	1.79	0.51–6.28	0.369
	Current smoker	0.84	0.21–3.41	0.827	1.74	0.78–3.87	0.175
	Diabetes	0.88	0.27–2.84	0.827	1.16	0.46–2.90	0.754
	ABSIe (from 1 SD)	3.20	1.60–6.42	0.001	1.09	0.53–2.22	0.817

HR hazard ration, yrs years, SD standard deviation

^aC statistics (95 % CI): 0.634 (0.527–0.710) for women; 0.675 (0.575–0.775) for men

^bC statistics (95 % CI): 0.626 (0.521–0.731) for women; 0.644 (0.541–0.746) for men

^cC statistics (95 % CI): 0.611 (0.506–0.717) for women; 0.631 (0.528–0.734) for men

^dC statistics (95 % CI): 0.685 (0.581–0.789) for women; 0.627 (0.525–0.728) for men

^eABSI (1 ± SD, male 0.0062 and female 0.0069)