Table 1.

The main clinical and laboratory parameters of the patient and control groups

Parameters	Patients (n = 105)	Controls (n = 109)
Age ***	64.2 ± 0.98	57.0 ± 1.34
Gender (male)	84 (80)	75 (69)
Diabetes	32 (30.5)	23 (21.1)
Hypertension ***	92 (87.6)	44 (40.4)
Stroke history	12 (11.4)	6 (5.5)
Myocardial infarction history	11 (10.4)	18 (16.5)
CAD***	72 (68.6)	40 (36.7)
Intermittent claudication	105 (100)	no
Critical limb ischemia	30 (28.6)	no
Significant carotid stenosis a	10 (13.5)	nd
Multiple atherosclerotic involvement***	21 (20)	4 (3.7)
Haemorheological treatment	105 (100)	no
Antihypertensives ***	87 (82.8)	29 (26.6)
Anticoagulants **	25 (23.8)	10 (9.2)
Statins ***	73 (69.5)	10 (9.2)
Fibrates	10 (9.5)	4 (3.7)
Rate of AB0 blood groups (0/non-0)	0.38	0.49
ABI (lower)	0.48 (0.36–0.60)	nd
ABI (mean)	0.59 (0.43–0.73)	nd
CIMT (lower) a	1.00 (0.70–1.30)	nd
CIMT (mean) a	1.25 (0.7–1.45)	nd
OPG [ng/mL] ***	4.64 (3.49–6.54)	3.68 (2.92–4.81)
VWF:Ag [%]	129 (96–174)	116 (94–150)
VWF:CB [%] *	123 (94–163)	107 (88–136)
Fibrinogen [g/L] ***	4.10 (3.04–5.03)	3.00 (2.32–3.50)
Total cholesterol [mmol/L]	4.83 (3.98–5.87)	5.10 (4.29–5.88)
HDL–cholesterol [mmol/L] ***	1.19 (1.03–1.40)	1.52 (1.28–1.74)
Triglycerides [mmol/L]	1.33 (0.96–1.76)	1.20 (0.86–1.74)
CRP [mg/L]	5.03 (2.22–9.67)	4.44 (1.84–6.55)

Age is expressed as mean ± SE, gender as the number of males and their percentage, disease states as number and percentage in brackets, compared to all individuals of the group, parameters are given as median with quartile range in brackets. * p < 0.05, ** p < 0.01, *** p < 0.001 significances of patients to control (Mann–Whitney U test for continuous variables and Fisher’s exact test for categorical variables), ^aexamined in 74 cases, no = no sign or history at controls, nd = not determined