Table 3.
Univariate (chi-square) and multivariate (logistic regression) analysis for clinicopathological features associated with late recurrence after completion of 5 years tamoxifen
Variables | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
P value | Odds ratio | 95 % CI | P value | |
Age (<50 vs ≥ 50 Years) | 0.098 | 0.981 | 0.954–1.008 | 0.168 |
Menopausal status (pre-vs-post-) | 0.409 | |||
Tumor size (>2 cm vs ≤2 cm) | 0.002 | 1.297 | 0.762–2.207 | 0.338 |
ALNa metastasis (yes vs no) | <0.001 | 2.731 | 1.615–4.618 | <0.001 |
PgRb (negative vs posituve) | 0.420 | |||
HER2 (positive vs negative) | 0.051 | |||
Histologic grade (Gr III vs Gr I or II) | 0.018 | 1.396 | 0.786–2.479 | 0.256 |
Ki-67 (high vs low)c | 0.480 | |||
Radiotherapy (yes vs no) | 0.134 | |||
Chemotheraphy (yes vs no) | 0.434 |
aALN axillary lymph node
bPgR progesterone
cThe cutoff values of Ki-67 are 14 % in NCC and 10 % in SNUH [26]