Table 1.
Characteristics of patients undergoing stereotactic ablative radiotherapy (SABR) or thoracoscopic sublobar lung resection (SLR) for tumor sized ≤2 cm. Figures are numbers (percentage) of patients unless specified
| Variable | SABR (n=275) | Thoracoscopic SLR (n=415) | P value |
|---|---|---|---|
| Mean (SD) age (years) | 77.6 (6.3) | 75.6 (5.8) | <0.001 |
| Men | 98 (35.6) | 161 (38.8) | 0.40 |
| Women | 177 (64.4) | 254 (61.2) | |
| Race: | |||
| White | 241 (87.6) | 379 (91.3) | 0.12 |
| Black/other/unknown | 34 (12.4) | 36 (8.7) | |
| Marital status: | |||
| Unmarried | 138 (50.2) | 180 (43.4) | 0.19 |
| Married (or with partner) | 126 (45.8) | 219 (52.8) | |
| Unknown | 11 (4.0) | 16 (3.9) | |
| Location: | |||
| Metropolitan | 239 (86.9) | 368 (88.7) | 0.49 |
| Non-metropolitan | 36 (13.1) | 47 (11.3) | |
| SEER registry region: | |||
| Northeast | 55 (20.0) | 121 (29.2) | 0.03 |
| Midwest | 51 (18.5) | 55 (13.3) | |
| South | 67 (24.4) | 100 (24.1) | |
| West | 102 (37.1) | 139 (33.5) | |
| Median quarter of income distribution (2000 census): | |||
| 1 (lowest income) | 76 (27.7) | 88 (21.3) | 0.16 |
| 2 | 66 (24.1) | 95 (22.9) | |
| 3 | 75 (27.4) | 123 (29.7) | |
| 4 | 57 (20.8) | 108 (26.1) | |
| Tumor T stage: | |||
| T1 | 261 (94.9) | 348 (83.9) | <0.001 |
| T2 | 14 (5.1) | 67 (16.1) | |
| Tumor histology: | |||
| Adenocarcinoma | 144 (52.4) | 197 (47.5) | <0.001 |
| Squamous | 113 (41.1) | 109 (26.3) | |
| Other | 18 (6.5) | 109 (26.3) | |
| Tumor grade: | |||
| Grade I | 27 (9.8) | 99 (23.9) | <0.001 |
| Grade II | 47 (17.1) | 185 (44.6) | |
| Grade III-IV | 58 (21.1) | 101 (24.3) | |
| Not determined | 143 (52.0) | 30 (7.2) | |
| Tumor size ≤1 cm: | |||
| 0-10 mm | 24 (8.7) | 103 (24.8) | <0.001 |
| 11-20 mm | 251 (91.3) | 312 (75.2) | |
| Procedure type: | |||
| Wedge resection | — | 363 (87.5) | — |
| Segmental resection | — | 52 (12.5) | |
| Year of procedure: | |||
| 2007-08 | 37 (13.5) | 113 (27.2) | <0.001 |
| 2009-10 | 121 (44.0) | 189 (45.5) | |
| 2011-12 | 117 (42.5) | 113 (27.2) | |
| Pre-procedure PET scan or mediastinoscopy | 203 (73.8) | 161 (38.8) | <0.001 |
| Comorbidities (Elixhauser34): | |||
| Coronary artery disease | 141 (51.3) | 234 (56.4) | 0.19 |
| Hypertension | 236 (85.8) | 355 (85.5) | 0.92 |
| Congestive heart failure | 78 (28.4) | 94 (22.7) | 0.09 |
| Valve disease | 76 (27.6) | 122 (29.4) | 0.62 |
| Diabetes | 92 (33.5) | 164 (39.5) | 0.11 |
| Chronic pulmonary disease | 244 (88.7) | 333 (80.2) | 0.003 |
| Obesity | 19 (6.9) | 29 (7.0) | 0.97 |
| Anemia | 104 (37.8) | 133 (32.0) | 0.12 |
| Peripheral vascular disease | 133 (48.4) | 182 (43.9) | 0.24 |
| Chronic kidney disease | 47 (17.1) | 57 (13.7) | 0.23 |
| Cerebrovascular disease | 76 (27.6) | 109 (26.3) | 0.69 |
| Weight loss | 42 (15.3) | 40 (9.6) | 0.03 |
| Neurologic disorder | 74 (26.9) | 54 (13.0) | <0.001 |
| Hypothyroidism | 82 (29.8) | 105 (25.3) | 0.19 |