Table 2.
Parameter Level | Crudea Est. (95% CI) |
p–value | Adjusteda Est. (95% CI) |
p–value |
---|---|---|---|---|
Sex | ||||
Male | Ref. | – | Ref. | – |
Female | –10 (–15 to –5) | 0.06 | –11 (–17 to –5) | 0.07 |
Age per 5-year increment | –1.5 (–3 to –0.3) | 0.2 | –0.7 (–2 to 0.9) | 0.7 |
BMI per 5-unit increment | –4.2 (–7 to –2) | 0.09 | –7.1 (–10 to –4) | 0.02 |
Race | ||||
White | Ref. | – | Ref. | – |
Hispanic | 18 (9 to 27) | 0.04 | 18 (8 to 27) | 0.06 |
Black | 15 (6 to 24) | 0.1 | 13 (3 to 23) | 0.2 |
Asian | –20 (–34 to –5) | 0.2 | –27 (–42 to –11) | 0.09 |
Other | 57 (30 to 83) | 0.03 | 73 (43 to 103) | 0.02 |
Unknown | –8.5 (–47 to 30) | 0.8 | –52 (–127 to 23) | 0.5 |
Diabetes | 6.6 (–0.1 to 13) | 0.3 | 11 (3 to 19) | 0.2 |
Comorbidity | ||||
Congestive heart failure | 6.5 (–11 to 24) | 0.7 | 7.6 (–11 to 26) | 0.7 |
Valvular disease | –3.7 (–18 to 11) | 0.8 | –3.8 (–19 to 11) | 0.8 |
Pulmonary circulation disease | 13 (–19 to 45) | 0.7 | 21 (–13 to 54) | 0.5 |
Peripheral vascular disease | –9.2 (–19 to 1) | 0.4 | –9.9 (–20 to 0.6) | 0.3 |
Paralysis | –60 (–19 to 101) | 0.1 | –58 (–99 to –17) | 0.2 |
Other neurological disorders | –27 (–44 to –10) | 0.1 | –23 (–41 to –6) | 0.2 |
Chronic pulmonary disease | 2.5 (–6 to 11) | 0.8 | 6.7 (–1 to 15) | 0.4 |
Hypothyroidism | –11 (–19 to –2) | 0.2 | –4.4 (–13 to 4) | 0.6 |
Renal failure | –17 (–27 to –8) | 0.08 | –14 (–24 to –4) | 0.1 |
Liver disease | 21 (2–40) | 0.3 | 16 (–4 to 35) | 0.4 |
Peptic ulcer | – | – | – | – |
AIDS | 238 (166 to 310) | 0.001 | 224 (152 to 297) | 0.002 |
Lymphoma | 29 (–14 to 73) | 0.5 | 15 (–29 to 58) | 0.7 |
Metastatic cancer | –49 (–95 to –3) | 0.3 | –46 (–92 to –0.6) | 0.3 |
Solid tumor w/o metastasis | 54 (27 to 80) | 0.04 | 52 (25 to 78) | 0.05 |
Rheumatoid arthritis | 3.4 (–13 to 20) | 0.8 | 5 (–11 to 21) | 0.8 |
Coagulopathy | –10 (–29 to 9) | 0.6 | –16 (–36 to 3) | 0.4 |
Weight loss | 36 (7 to 64) | 0.2 | 27 (–2 to 56) | 0.4 |
Fluid and electrolyte disorders | 8.1 (–4 to 20) | 0.5 | 12 (0.2 to 24) | 0.3 |
Chronic blood loss anemia | 5.7 (–10 to 21) | 0.7 | 8 (–8 to 24) | 0.6 |
Deficiency anemias | 24 (15 to 32) | 0.01 | 25 (17 to 34) | 0.004 |
Alcohol abuse | 13. (–5 to 32) | 0.5 | 16 (–3 to 35) | 0.4 |
Drug abuse | 6.7 (–16 to 30) | 0.8 | 4.2 (–19 to 28) | 0.9 |
Psychoses | –40 (–52 to –28) | 0.001 | –38 (–50 to –27) | 0.001 |
Depression | 7.2 (–5 to 20) | 0.6 | 4.9 (–8 to 18) | 0.7 |
Hypertension | –8.3 (–14 to –3) | 0.2 | –6 (–12 to 0.4) | 0.3 |
BMI: body mass index; AIDS: acquired immunodeficiency syndrome.
Crude models, n = 5,678; adjusted model, n = 4,926, due to n = 752 (13.2%) missing comorbidity data.