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. Author manuscript; available in PMC: 2016 Jul 8.
Published in final edited form as: J Neurosci Res. 2008 Nov 15;86(15):3265–3274. doi: 10.1002/jnr.21787

Figure 2.

Figure 2

Effects of diabetes on insulin receptor phosphorylation. (A) Western blots of brain homogenates from mice diabetic for 9 weeks for phosphorylated insulin receptor (pIR, upper band), insulin receptor (IR) and actin. (B) Intensity of bands corresponding to phosphorylated and total insulin receptor. Data for control (C) mice are represented by white bars, for diabetic (D) mice at 4 weeks (4w) of diabetes by grey bars and at 9 weeks (9w) of diabetes by black bars. Data are mean+SEM, n=7/group. pIR/IR is the ratio of the intensity of the bands corresponding to phosphorylated insulin receptor over the intensity of the bands corresponding to total insulin receptor. pIR/Actin is the ratio of the intensity of the bands corresponding to phosphorylated insulin receptor over the intensity of the bands corresponding to actin. IR/Actin is the ratio of the intensity of the bands corresponding to total insulin receptor over the intensity of the bands corresponding to actin. *p<0.05; **p<0.01 by one-way Anova versus control, followed by Bonferronni’s post-hoc test.