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The absolute value of the normalized bias of the proposed ML, LR and ADC-map estimation techniques in estimating ADC values of heterogeneous lesions. Models investigated include (a)–(b) lesion with uniform distribution of ADC values (c)–(d) rim lesion model (e)–(f) variegated lesion model. The left and right side plots study the variation with lesion SNRb0 and lesion size, respectively. The error bars denote 95% confidence intervals.
