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. 2015 Dec 18;124(7):1034–1041. doi: 10.1289/ehp.1510308

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Proposed global network for potential converging genes associated with diabetes/insulin resistance, obesity, or metabolic syndrome X, and the three POPs. Thick lines highlight the closest interactions. Large gray circles represent union genes. Small red circles indicate the intersection genes for the three diseases. Symbols defined by MetaCore™ at http://lsresearch.thomsonreuters.com/static/uploads/files/2014-05/MetaCoreQuickReferenceGuide.pdf: green arrows, activating interactions; red arrows, inhibiting interactions; POPs, purple hexagons; catalytic factors, yellow; transcription factors, red; cytokines and lipoproteins, green; receptors and adaptor proteins, blue.