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. 2015 Dec 18;124(7):1034–1041. doi: 10.1289/ehp.1510308

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Activation of TNF-α. Thick lines highlight the closest interactions, and thin lines indicate intermediate and farther interactions. AHR, aryl hydrocarbon receptor; PXR, pregnane X receptor. Symbols defined by MetaCore™ at http://lsresearch.thomsonreuters.com/static/uploads/files/2014-05/MetaCoreQuickReferenceGuide.pdf: green arrows, activating interactions; red arrows, inhibiting interactions; POPs, purple hexagons; TNF-α, green symbol; transcription factors, red symbols.