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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Immunol Rev. 2016 Jul;272(1):183–201. doi: 10.1111/imr.12430

Figure 1.

Figure 1

CD4+ T cells recognize distinct registers of the B:9–23 peptide. Response of the hybridomas IIT-3 (Left Panel) and 9B9 (Right Panel) to the Register 1, B:12–20 and the Register 2, B:13–21 peptides covalently linked to I-Ag7 expressed on C3.G7 cells. T cells directed to Register 1, B:12-20 escape negative selection and can enter islets.

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