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. 2016 Jul 8;11(7):e0158639. doi: 10.1371/journal.pone.0158639

Table 1. Comparison of overall median survivals according to strain, age and route.

Mice Cells Age Route a Cell No. Cell form Event b Number of mice Median survivals c
Balb/c-nu 578T 6 weeks I.C. 2×105 w/ HBSS Debility 10 77
Balb/c-nu 578T 6 weeks S.C. 2×106 w/ HBSS Neoplasm 10 80
NOD/SCID 578T 6 weeks I.C. 2×105 w/ HBSS Debility 10 62
NOD/SCID 578T 6 weeks S.C. 2×106 w/ HBSS Neoplasm 10 68
Neonate NOG 578T 1 week I.C. 2×105 w/ HBSS Debility 10 45
Neonate NOG 578T 1 week S.C. 2×106 w/ HBSS Neoplasm 10 54
Adult NOG 578T 6 weeks I.C. 2×105 w/ HBSS Debility 10 60
Adult NOG 578T 6 weeks S.C. 2×106 w/ HBSS Neoplasm 10 70

a. I.C.: Intracranial injection, S.C.: Subcutaneous injection

b. None: Not happened anything, Debility: decrease of weight and bad condition, Neoplasm: neoplasm into injection site

c. I.C. survivals: Condition and body weight, S.C. survivals: tumor volume ≥ 1,500 mm3