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Efficiency of NHEJ and HDR editing in CRISPR-EZ edited mice
| CRISPR-EZ pulse length | Mice assayed by RFLP | Type of editing events detected by RFLP analyses |
|||||
|---|---|---|---|---|---|---|---|
| Unedited | Unedited, NHEJ | Unedited, HDR | NHEJ, HDR | Bi-allelic NHEJ | Bi-allelic HDR | ||
| 1 ms | 44 | 18 (41%) | 6 (14%) | 2 (5%) | 8 (18%) | 8 (18%) | 2 (5%) |
| 3 ms | 31 | 0 | 2 (6%) | 1 (3%) | 11 (35%) | 16 (52%) | 1 (3%) |
