FIGURE 3.

Antibodies specific for αv and β1 integrin block the fusogenic activity of the aMPV/B F protein and aMPV/B replication. A and B, in the presence of integrin-specific antibodies, aMPV/B F protein fusogenic activities were measured by syncytium formation and reporter gene assays. C–E, the replication of aMPV/B in the presence of integrin-specific antibodies in Vero, BHK-21, and DF-1 cells, respectively, was evaluated. The virus titer was measured at 48 h.p.i. All experiments were repeated three to five times. p < 0.05 and p < 0.005 are indicated by * and **, respectively.