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. 2016 Jul 4;11:1521–1532. doi: 10.2147/COPD.S107938

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© 2016 Otani et al. This work is published and licensed by Dove Medical Press Limited

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UIP pattern on thin-section CT images and histological findings.

Notes: (A and B) Thin-section CT images showing clustered cysts of similar size and shape. Note surrounding ground-glass attenuation with reticular opacity. (C) This low-power photograph of the histological section (hematoxylin–eosin stain) reveals macroscopic honeycombing (asterisk) corresponding to honeycombing on thin-section CT images and patchy fibrosis with architectural distortion and microscopic honeycombing reflecting ground-glass attenuation with reticular opacity. (D) Note dense fibrosis and fibroblastic foci (arrow) on high-power photographs of the histological section. (E) Masson’s trichrome stain reveals architecture destruction with scattered fibroblastic foci (arrow).

Abbreviations: UIP, usual interstitial pneumonia; CT, computed tomography.