Table 1.

IC50s (in nM) for the various HDACi and cell lines are depicted with corresponding 95% confidence intervals.

	GL261	3T3	Neuro-2a	9464D	975A2
Vorinostat	>16,000	3,535 (2,175–5,745)	1,446 (882–2,372)	608 (540–683)	657 (446–969)
Givinostat	>16,000	5,111 (3,122–8,368)	2,426 (1,603–3,671)	1504 (1,207–1,874)	980 (753–1,275)
Belinostat	>16,000	627 (396–992)	579 (482–695)	84 (54–130)	58 (47–71)
PCI-24781	>16,000	363.7 (225–587)	406 (208–794)	138 (96–199)	89 (79–102)
Entinostat	>16,000	>16,000	13,453 (6,941–26,075)	2,997 (2,245–4,000)	1,001 (555–1,804)
HDAC1,2	>16,000	587 (360–957)	408 (184–903)	468.5 (393–558)	194.8 (141–297)
Tubacin	9,362 (5,416–16,085)	7,207 (4,710–11,029)	4,064 (6,010–22,358)	9,710 (4,222–22,382)	2,737 (2,198–3,408)
HDAC6	>16,000	9,948 (4,925–20,093)	4,807 (2,182–10,591)	10,837 (3,584–12,652)	4,099 (1,830–6,459)