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. 2016 Mar 16;5(6):e1160193. doi: 10.1080/2162402X.2016.1160193

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Figure 1. — Prognostic impact of individual immune parameters and ratios between effector and suppressor cells measured by immunohistochemistry in melanoma metastases. (A) Impact of immune parameters on hazard ratios. The hazard ratios were calculated in an unadjusted (u) or adjusted (a) fashion for each of the indicated individual immune parameters or for the indicated ratios (each time after having calculated optimal cut-offs using log-rank statistics). Results are plotted together with the 95% confidence intervals. (B–E) Kaplan Meyer survival plots exemplifying the effects of distinct ratios between effector and suppressor cells on overall patient survival. Hazard ratios (HR) are indicated as unadjusted or adjusted values.