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. 2016 Mar 23;5(6):e1146841. doi: 10.1080/2162402X.2016.1146841

Figure 1.

Figure 1.

Rictor−/− BMDC display pro-inflammatory properties. (A) CD11c+-gated BMDC were analyzed for cell surface MHC class-II (I-Ab), CD40, CD86, B7-H1 (PD-L1) and CCR7 expression by flow cytometry following 6 d culture in the absence of stimulation (−) or after LPS stimulation (LPS) for the last 18 h of culture. Plots show the means and individual values of n = 3–6 mice. (B) Cytokine levels in supernatants were assessed by cytokine bead array (IL-6, TNFα, MCP-1) or ELISA (IL-12p70 and IFNγ). Data are from n = 4–6 mice. #p < 0.05 compared to corresponding non-stimulated cells; *p < 0.05 and **p < 0.01 between control and Rictor−/− DC.