Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 May 5;5(6):e1153208. doi: 10.1080/2162402X.2016.1153208

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

PMC Copyright notice

Figure 3. — Significantly more sTIL within the primary tumor than mTIL within the site of the corresponding metastasis. Bar graphs for CD4⁺, CD8⁺ and CD20⁺ stromal infiltrating lymphocyte subsets show that there are significantly more sTIL within the primary tumor than mTIL within the site of the corresponding metastasis irrespectively of the anatomical site of distant metastasis (A–D). The distribution of infiltrating lymphocytes is schematically visualized with respect to the three primary tumor/metastasis compartments (E) consisting of intratumoral lymphocytes (iTIL_PT/iTIL_Met = white dots), stromal lymphocytes (sTIL_PT/sTIL_Met = gray dots) and invasive margin lymphocytes (imTIL_PT/imTIL_Met = black dots) and with respect to the lymphocyte subsets within these compartments (F) comprising CD4⁺ infiltrating lymphocytes (red dots), CD8⁺ infiltrating lymphocytes (green dots) and CD20⁺ infiltrating lymphocytes (blue dots). Significances are displayed as follows: ns = p > 0.05, *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 and ****p ≤ 0.0001.