Table 3.
Distribution of metastasis infiltrating lymphocytes (mTIL) subsets within the site of metastasis. Mean and median are displayed for CD4+, CD8+ and CD20+ lymphocytes within the two investigated metastasis compartments consisting of intratumoral (iTIL) and stromal (sTIL) divided into the four anatomical sites (brain, bone, liver and soft tissue) of the corresponding metastasis.
| Site of Metastasis |
||||||||
|---|---|---|---|---|---|---|---|---|
| Brain (n = 21) |
Bone (n = 24) |
Liver (n = 11) |
Soft tissue (n = 31) |
|||||
| TIL within the site of metastasis | Mean | Median | Mean | Median | Mean | Median | Mean | Median |
| iCD4+ T cells | 2.3 | 2.0 | 1.2 | 0.3 | 0.8 | 0.3 | 7.3 | 5.0 |
| iCD8+ T cells | 3.1 | 2.0 | 2.8 | 0.7 | 1.1 | 0.7 | 4.9 | 3.7 |
| iCD20+ B cells | 0.4 | 0.3 | 0.3 | 0.3 | 0.3 | 0.3 | 1.2 | 0.3 |
| sCD4+ T cells | 7.9 | 7.0 | 4.9 | 2.2 | 2.6 | 0.7 | 15.1 | 8.3 |
| sCD8+ T cells | 6.2 | 6.7 | 3.2 | 2.2 | 4.4 | 5.0 | 10.5 | 8.3 |
| sCD20+ B cells | 1.8 | 0.3 | 0.6 | 0.3 | 0.5 | 0.3 | 5.2 | 2.0 |