Table 1. Characteristics of participants stratified by groupsa.
| Groups | |||||
|---|---|---|---|---|---|
| ELSA | Friend Controls | HIV | Total | P value | |
| Total | 10943 | 88 | 535 | 11566 | |
| Sex: Male | 4880 (44.59) | 31 (35.23) | 306 (57.2) | 5217 (45.11) | < 0.001 |
| Age in years—median(IQR) | 51 (45,58) | 44.48 (36.62,54.61) | 43.59 (36.34,51.01) | 51 (45,58) | < 0.001 |
| Schooling: <9 years | 1409 (12.88) | 51 (57.95) | 259 (48.41) | 1719 (14.86) | < 0.001 |
| Black Race: Yes | 4349 (40.19) | 55 (62.5) | 341 (63.74) | 4745 (41.47) | < 0.001 |
| Smoking | < 0.001 | ||||
| Never | 6214 (56.79) | 51 (57.95) | 271 (50.65) | 6536 (56.52) | |
| Former | 3271 (29.89) | 20 (22.73) | 142 (26.54) | 3433 (29.68) | |
| Current | 1457 (13.32) | 17 (19.32) | 122 (22.8) | 1596 (13.8) | |
| Packs.year (10+) | 2577 (23.66) | 20 (22.73) | 143 (26.78) | 2740 (23.8) | 0.2481 |
| Income (R$)—median(IQR) | 1347.12 (725.38,2279.75) | 414.5 (207.25,656.29) | 414.5 (207.25,1036.25) | 1312.58 (690.83,2279.75) | < 0.001 |
| Family History of Sudden Death | 1652 (15.1) | 11 (12.5) | 105 (19.63) | 1768 (15.29) | 0.0135 |
| Family History of AMI or Stroke | 2939 (26.86) | 31 (35.23) | 148 (27.66) | 3118 (26.96) | 0.1972 |
| History of CVD | 575 (5.25) | 7 (7.95) | 38 (7.1) | 620 (5.36) | 0.0997 |
| Total cholesterol (mg/dL)—median(IQR) | 211 (186,239) | 186.5 (162,214.25) | 182 (156,210) | 210 (184,238) | < 0.001 |
| HDL (mg/dL)—median(IQR) | 54 (46,65) | 44.5 (39,53) | 42 (35,52) | 54 (46,65) | < 0.001 |
| LDL (mg/dL)—median(IQR) | 128 (107,152) | 115 (96.75,139) | 106 (87,133) | 128 (106,151) | < 0.001 |
| Triglycerides (mg/dL)—median(IQR) | 113 (80,162) | 98 (68.5,135) | 120 (85,185) | 113 (81,163) | < 0.001 |
| Dyslipidemia | 6315 (57.73) | 35 (39.77) | 199 (38.05) | 6549 (56.7) | < 0.001 |
| Use of lipid-lowering drugs | 1417 (12.95) | 6 (6.82) | 74 (13.83) | 1497 (12.94) | 0.1916 |
| Hypertension | 3936 (35.97) | 37 (42.05) | 168 (31.4) | 4141 (35.8) | 0.0466 |
| DM | 1905 (17.41) | 30 (34.09) | 131 (24.49) | 2066 (17.86) | < 0.001 |
| Waist circumference (cm)- median(IQR) | 89.9 (81.5,98.5) | 90 (84,98.53) | 85.7 (78,94.05) | 89.7 (81.4,98.3) | < 0.001 |
| BMI—median(IQR) | 26.43 (23.81,29.55) | 27.51 (24.13,30.1) | 24.35 (21.83,27.2) | 26.33 (23.7,29.46) | < 0.001 |
| hs-CRP (mg/dL)—median(IQR) | 1.42 (0.7,3.25) | 0.32 (0.2,0.6) | 0.29 (0.18,0.64) | 1.33 (0.64,3.09) | < 0.001 |
| eGFR (mL/min/1.73m2)- median(IQR) | 88.25 (76.14,101.04) | 99.18 (81.51,109.13) | 106.27 (92.57,120.5) | 88.98 (76.48,102.07) | < 0.001 |
| Poor management: Yes | 5776 (52.8) | 46 (52.27) | 233 (43.96) | 6055 (52.39) | < 0.001 |
| cIMT (mm)—median(IQR) | 0.58 (0.52,0.68) | 0.57 (0.49,0.7) | 0.54 (0.49,0.62) | 0.58 (0.52,0.68) | < 0.001 |
a Numbers are N (%) unless noted otherwise
Abbreviations: IQR–interquartile range; AMI–acute myocardial infarction; CVD–cardiovascular disease; BMI–body mass index; DM–diabetes mellitus; HDL–high density lipoprotein; LDL–low density lipoprotein; hs-CRP high sensitivity C-reactive protein; CMV–cytomegalovirus.