Table 2. Histopathological findings.

Histological analysis of the liver at each experimental checkpoint times according to Brunt's classification. Data is expressed as score/grade and between brackets the occurrence.

	MALE				FEMALE
Parameters	4 weeks	8 weeks	12 weeks	16 weeks	4 weeks	8 weeks	12 weeks	16 weeks
Steatosis Grade (0–3)	1 (33%); 2(66%)	2 (100%)	2 (100%)	2 (33%); 3 (66%)	2 (100%)	2 (100%)	2 (33%); 3 (66%)	1 (29%); 2 (71%)
Location (score 0–3)	2; Azonal	2; Azonal	2; Azonal	3; Paracinar	2; Azonal	2; Azonal	2 (33%); Azonal. 3 (66%); Paracinar	1 (29%); periportal. 2 (71%); Azonal
Portal Inflammation (score 0–1)	0 (100%)	0 (66%); 1 (33%)	0 (100%)	0 (62%); 1 (28%)	0 (66%); 1 (33%)	0 (66%); 1 (33%)	0 (66%); 1 (33%)	0 (58%); 1 (42%)
Lobular Inflammation Score (0–3)	0 (66%); 1 (33%)	0 (33%); 1 (33%); 2 (33%)	0 (33%); 1 (66%)	0 (15%); 1 (85%)	0 (33%); 1 (66%)	0 (33%); 1 (66%)	0 (33%); 1 (66%)	0 (72%); 1 (28%)
Fibrosis Stage (0–4)	0 (66%); 1a (33%)	1b (66%); 1c (33%)	1a (33%); 1c (66%)	1a (14%); 2 (86%)	0 (66%); 1a (33%)	1a (66%); 1b (33%)	1a (33%); 1b (33%); 2 (33%)	1b (14%); 1c (71%); 2 (15%)