. 2016 Jul 8;11(7):e0158179. doi: 10.1371/journal.pone.0158179

Table 1. The results (median, IQR) are given separately for the CVVHDF (the first row) and CVVH (the second row) subgroups.

Differences between CVVHDF and CVVH reached statistical significance for post to pre-filter citrate difference (p<0.05) at T9(Mg1.50), T27(Mg1.50) and for Mg balance at T27(Mg1.50) (p = 0.02). Comparisons between T0(Mg0.75) and T9(Mg1.50), T18(Mg1.50), T27(Mg1.50) are given separately for CVVHDF and CVVH where statistically significant.

CVVHDF (n = 22) CVVH (n = 23)	T0(Mg0.75): Qb 100 ml/min 2000 ml/h	T9(Mg1.50): Qb 100 ml/min 2000 ml/h	T18(Mg1.50): Qb 150 ml/min 2000 ml/h	T27(Mg1.50): Qb 150 ml/min 3000 ml/h
4%TSC dose [ml/h]	200 (180–230)	200 (180–233)	300 (248–350)^A^,^B	300 (240–345)^A^,^B
4%TSC dose [ml/h]	200 (180–220)	200 (190–230)	305 (243–338)^A^,^B	260 (250–345)^A^,^B
Dose of 4%TSC/Qb [mmol/l.h]	4.4 (4.1–5.4)	4.5 (4.1–5.3)	4.5 (3.7–5.3)	4.5 (3.6–5.2)
Dose of 4%TSC/Qb [mmol/l.h]	4.5 (4.1–5.2)	4.5 (4.3–5.2)	4.6 (3.7–5.1)	3.9 (3.8–5.2)
Post to pre- filter citrate [mmol/l]	3.49 (2.57–4.5)	2.90 (2.62–3.47)	3.29 (2.32–3.91)	3.51 (2.45–3.86)
Post to pre- filter citrate [mmol/l]	4.25 (3.46–5.11)	4.25 (3.64–4.86) (p<0.05)	3.75 (3.32–4.52)	3.92 (3.30–4.72) (p<0.05)
Citrate filter removal [%]	49.9 (43.8–54)	47.1 (40.4–53)	34.4 (29–36.3)^A^,^B	47.5 (38.9–54)^C
Citrate filter removal [%]	46.8 (39.9–49.6)	41.9 (37.5–49.5)	33.9 (31–37.2)^A^,^B	43.1 (38.8–47)^C
Ca_tot [mmol/l]	2.27 (2.07–2.47)	2.05 (1.78–2.4)	2.31 (1.83–2.75)	2.07 (1.82–2.37)
Ca_tot [mmol/l]	2.1 (1.82–2.46)	2.01 (1.86–2.31)	2.16 (1.87–2.52)	1.96 (1.79–2.16)
Ca²⁺ [mmol/l]	1 (0.87–1.08)	1.04 (0.97–1.1)	1.02 (0.93–1.11)	0.98 (0.93–1.04)
Ca²⁺ [mmol/l]	1 (0.97–1.05)	1.05 (1–1.08)	1.06 (0.95–1.12)	0.96 (0.92–1.02)
Ca index [Ca_tot/Ca²⁺]	2.12 (1.95–2.35)	1.97 (1.83–2.18)	2.26 (1.97–2.48)	2.11 (1.95–2.28)
Ca index [Ca_tot/Ca²⁺]	2.12 (1.88–2.34)	1.98 (1.87–2.14)	2.04 (1.97–2.26)	2.04 (1.95–2.12)
Ca balance [mmol/h]	3.12 (1.89–3.74)	4.29 (2.89–5.17)	4.09 (3.16–5.71)	3.02(2.46–4.86)
Ca balance [mmol/h]	3.05 (1.97–4.78)	3.57 (2.24–6.16)	3.34 (2.24–5.69)	2.40 (1.26–4.27)
Mg_tot [mmol/l]	1.09 (0.95–1.19)	1.23(1.16–1.31)^A	1.29(1.18–1.35)^A	1.33(1.26–1.38)^A,D
Mg_tot [mmol/l]	1.04 (0.95–1.19)	1.2 (1.13–1.28)^E	1.23 (1.2–1.31)^A	1.28 (1.2–1.36)^A^,^D
Mg balance [mmol/h]	-1.02 (-1.2 to -0.54)	0.17(-0.02–0.32)^A	-0.02 (-0.23–0.19)^B	-0.06 (-0.20–0.18)^B
Mg balance [mmol/h]	-0.80 (-0.91 to -0.56)	0.24(0.09–0.35)^A	-0.03(-0.05 to -0.17)^B	0.18 (0.03–0.37)^E

^A significantly different from T0, p<0.01

^B significantly different from T9, p<0.01

^C significantly different from T18, p<0.05

^D significantly different from T9, p<0.05

^E significantly different from T0, p<0.05