Table 2.
Baseline characteristics of patients undergoing CMR for CBF and APC flow
| All | Pre-BDG | BDG | Fontan | p Value | |
|---|---|---|---|---|---|
| Number of patients (N) | 106 pts, 118 scans | 34 | 50 | 34 | |
| Male/female | 72/46 (scans) | 20/14 | 27/23 | 25/9 | 0.193 |
| Age at CMR (years) | 2.8 (0.27, 8.4) | 0.41 (0.27, 2.01) | 3.06 (1.8, 7.6) | 3.6 (2.0, 8.4) | <0.001 |
| Weight (kg) | 12.7 (4.9, 28.0) | 6.3 (4.9, 9.2) | 12.8 (10.6, 28) | 15.5 (11.4, 27.7) | <0.001 |
| Height (cm) | 90.0 (36.0, 121.9) | 63.5 (57.0, 69.1) | 90.5 (36, 120) | 100.4 (83.8, 121.9) | <0.001 |
| BSA (m2) | 0.55 (0.26, 0.96) | 0.32 (0.26, 0.42) | 0.55 (0.49, 0.92) | 0.63 (0.53, 0.96) | <0.001 |
| Age at stage of surgery (years) | 0.01 (0.01, 0.07) | 0.42 (0.27, 0.70) | 3.1 (1.3, 7.6) | <0.001 | |
| Time: surgery to CMR (years) | 0.38 (0.27, 0.71) | 2.7 (1.4, 7.0) | 0.63 (0.33, 2.7) | <0.001 | |
| CPB time (min) | 82 (29, 147) | 62 (14, 102) | 62.5 (52, 124) | <0.001 | |
| Circ arrest time (min) | 42 (0, 76) | 18 (0, 45) | 23.5 (0, 49) | <0.001 | |
| Po2 RA (mm Hg) | 46 (36, 69) | 50.5 (34, 67) | <0.001 | ||
| Pco2 RA (mm Hg) | 40.0+4.8 | 38.6+4.9 | 0.11* | ||
| Po2 hypercarbia (mm Hg) | 51 (34, 93) | 61 (24, 79) | <0.001 | ||
| Pco2 hypercarbia (mm Hg) | 68 (35, 96) | 67 (33, 110) | 0.43 | ||
| Morphology | |||||
| DILV | 6 | 0 | 3 | 3 | 0.24 |
| DORV | 14 | 5 | 6 | 3 | 0.72 |
| HLHS | 64 | 19 | 27 | 18 | 0.97 |
| Heterotaxy | 6 | 0 | 3 | 3 | 0.24 |
| PA | 2 | 0 | 1 | 1 | 0.99 |
| PA/Intact Ventricular Septum | 2 | 1 | 1 | 0.99 | |
| SV with TGA | 4 | 1 | 1 | 2 | 0.82 |
| Tricuspid Atresia | 9 | 3 | 4 | 2 | 0.99 |
| Other SV | 11 | 5 | 4 | 2 | 0.52 |
All pre-BDG patients had a Blalock–Taussig shunt. All comparisons failed either normality or equal variance test and were compared with non-parametric testing with the exception of Pco2 in RA. Values expressed as mean±SD or median (minimum, maximum) depending upon whether the data were normally distributed or not.
APC, aortic-to-pulmonary collateral; BDG, bidirectional Glenn; BSA, body surface area; CBF, cerebral blood flow; Circ, circulatory; CMR, cardiac magnetic resonance; CPB, cardiopulmonary bypass; DILV, double inlet LV; DORV, double outlet RV; HLHS, hypoplastic left heart syndrome; N, number; PA, pulmonary atresia; Pco2, partial pressure of carbondioxide; Po2, partial pressure of oxygen; pts, patients; RA, room air; SV, single ventricle; TGA, transposition of the great arteries.