Table 3.
Flows measured in the aorta and systemic veins on room air and in hypercarbic conditions
| RA |
CO2 |
||||
|---|---|---|---|---|---|
| Flows (in L/min/m2) | Pre-BDG | BDG | Fontan | Pre-BDG | BDG |
| Aortic valve(s)* | 6.2 (3.0, 9.9) | 5.5 ( 3.6, 7.9) | 4.21±0.80 | 7.02±1.55 | 7.18±1.20 |
| Total jugular† | 1.42±0.44 | 1.78±0.49 | 1.28±0.54 | 1.98±0.54 | 2.39±0.54 |
| SVC‡ | 1.94±0.50 | 2.09±0.57 | 1.50±0.55 | 2.53±0.67 | 2.93±0.72 |
| IVC§ | 1.13 (0.48, 2.20) | 1.79 (0.87, 3.35) | 1.01 (0.62, 2.23) | 1.19 (0.51, 2.53) | 2.44 (1.19, 5.24) |
| DAo¶ | 1.28 (0.75, 2.77) | 1.58 (0.70, 2.80) | 1.2 (0.47, 1.98) | 1.48 (0.63, 2.26) | 2.36 (1.17, 4.72) |
| CBF (% Ao flow)** | 24.6±11.3 | 32.7±9.6 | 31.0±12.0 | 31.2±14.3 | 34.3±9.3 |
| APC flow using IVC (% Ao flow)†† | 50.1 (15.4, 74.0) | 29.74 (5.0, 50.0) | 34.9 (3.6, 75.9) | 46.6 (8.3, 68.19) | 22.2 (5.2, 42.5) |
| APC flow using DAo (% Ao flow)‡‡ | 44.1 (11.4, 72.5) | 31.2 (9.5, 56.1) | 34.4 (7.0, 62.1) | 38.3±17.2 | 28.5±13.3 |
Values expressed as mean±SD or median (minimum, maximum) depending upon whether the data was normally distributed or not.
RA flow significantly different between all three stages (p<0.001, non-parametric test).
RA flow of BDG significantly higher than Fontan and pre-BDG (p<0.01, parametric test) and hypercarbic flow of BDG significantly higher than pre-BDG (p=0.002, parametric test).
RA flow of Fontan significantly lower than pre-BDG and BDG (p<0.001, parametric test) and hypercarbic flow of BDG significantly higher than pre-BDG (p=0.01, parametric test).
RA flow of BDG significantly higher from Fontan and pre-BDG (p<0.001, non-parametric test) and hypercarbic flow of BDG significantly higher than pre-BDG (p<0.001, non-parametric test).
RA flow of BDG significantly higher from Fontan and pre-BDG (p<0.001, non-parametric test) and hypercarbic flow of BDG significantly higher than pre-BDG (p<0.001, non-parametric test).
RA flow significantly lower in pre-BDG than other two stages (parametric test).
RA and hypercarbic flow significantly higher in pre-BDG than other two stages (p<0.001, non-parametric test).
RA (p=0.03, non-parametric test) and hypercarbic flow (p=0.01, parametric test) significantly higher in pre-BDG than other two stages.
Ao, aorta; APC, aortic-to-pulmonary collateral; BDG, bidirectional Glenn; CBF, cerebral blood flow; CO2, carbon dioxide; DAo, descending aorta; IVC, inferior vena cava; RA, room air; SVC, superior vena cava.