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. 2016 Jul 8;11(7):e0158796. doi: 10.1371/journal.pone.0158796

Fig 6. Agonistic and biological activities of furanocoumarins.

Fig 6

(A) β-lactamase activity was measured in GPR119-CRE-bla CHO-K1 cells treated with the indicated concentrations of imperatorin, phellopterin or isoimperatorin for 5 h. (B) Active GLP-1 secretion in GLUTag cells. (C) Glucose-stimulated insulin secretion in INS-1 cells treated with the indicated concentrations of imperatorin or phellopterin in the presence of low (L, 3 mM) or high (H, 17.5 mM) glucose. n = 3-4/group. Values are means ± SE. *p <0.05, **p <0.01 compared with control group. #p<0.05, ##p<0.01 compared with vehicle-treated cells in the presence of high glucose.