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. 2016 Jul 8;11(7):e0158995. doi: 10.1371/journal.pone.0158995

Table 2. 32 noticeable occurrence frequency breakpoint regions (NOF-BPRs), which was found in at least 10% of all samples in the single tumor entities and/or the healthy tissues.

chr SNP A SNP B breast color. gastr. lung medul. ov. pro. renal normal class
2 172,338,300 172,339,964 7.96 14.29 0.29 1.72 2.26 8.21 0.00 7.34 0.69 3
172,345,151 172,348,021 4.51 14.29 0.00 1.37 1.63 7.73 0.00 7.34 0.69 3
4 3,027,493 3,027,897 0.00 0.00 11.47 0.00 0.00 0.00 0.00 1.83 1.39 3
3,029,623 3,035,631 0.00 0.00 11.76 0.00 0.00 0.00 0.00 1.83 1.16 3
9,994,215 9,996,852 12.47 0.00 1.47 1.37 0.00 0.00 0.00 3.67 0.00 2
9,997,801 10,001,833 13.79 0.00 7.35 3.44 0.00 0.00 0.00 3.67 0.00 2
5 4,430,296 4,431,868 0.27 0.00 11.18 0.69 0.00 0.00 0.00 0.00 1.16 1
4,443,854 4,445,976 0.27 0.00 18.53 2.06 0.00 0.00 0.00 0.00 0.93 3
61,569,169 61,572,989 0.00 0.00 0.00 0.34 1.09 0.00 0.00 12.84 0.46 2
126,152,745 126,158,200 0.27 0.00 0.00 1.37 1.54 0.00 0.00 10.09 1.16 3
6 67,048,629 67,049,406 2.39 12.70 2.65 2.75 1.18 0.48 0.00 4.59 0.46 2
77,422,497 77,439,868 7.16 10.05 2.35 5.15 6.07 4.83 1.67 5.50 3.24 3
7 35,396,655 35,397,567 0.00 0.00 1.03 3.82 0.27 11.59 5.83 0.00 8.33 3
8 6,104,977 6,107,427 1.59 15.87 1.18 1.03 1.36 5.31 0.00 8.26 0.23 2
39,225,941 39,288,762 7.69 12.17 4.71 8.25 8.79 4.35 0.83 9.17 5.56 3
39,397,732 39,398,022 7.43 11.11 4.71 8.25 8.79 4.83 0.83 9.17 5.09 3
43,778,914 46,924,211 9.02 3.70 2.65 7.22 0.63 8.21 14.17 5.50 3.01 3
9 9,337,599 9,338,146 0.27 0.53 13.53 0.34 0.00 0.00 0.00 0.00 0.46 1
9,338,417 9,339,871 0.27 0.53 11.76 0.69 0.00 0.00 0.00 0.00 0.46 1
10 44,051,819 44,065,519 0.53 0.00 0.00 1.03 0.36 0.00 0.00 10.09 0.23 2
11 9,241,448 9,250,359 1.06 1.06 0.29 1.72 2.90 0.97 0.00 11.01 0.93 3
14 35,070,371 35,076,347 0.00 0.00 0.00 0.34 0.45 0.00 0.00 10.09 0.46 1
16 70,842,097 70,854,381 15.38 0.00 0.29 1.03 1.81 0.48 0.00 0.00 0.23 2
85,082,710 85,091,864 0.27 4.76 0.29 0.34 15.58 1.45 0.00 10.09 0.23 2
85,091,864 85,092,483 11.14 22.75 9.41 26.12 27.90 21.26 0.00 11.01 4.86 3
85,092,748 85,092,892 9.81 27.51 9.71 25.43 43.48 22.71 0.00 21.10 5.09 3
17 18,917,513 18,917,915 1.86 1.59 0.29 0.69 10.05 0.00 0.00 0.00 0.00 2
18,917,915 19,168,912 0.53 0.53 0.00 0.00 15.40 0.00 0.00 0.00 0.00 1
18 4,976,160 4,979,612 0.27 16.40 4.12 0.00 1.36 0.00 0.00 25.69 11.81 3
4,989,683 4,990,804 0.27 11.64 2.35 0.00 2.08 0.00 2.50 20.18 11.34 3
21 23,655,764 23,655,900 0.00 0.53 10.00 12.03 0.63 5.31 3.33 0.00 6.71 3
23,664,658 23,667,121 0.53 2.65 11.47 13.40 3.62 11.59 7.50 0.92 9.03 3

BPRs are provided with their related chromosome (chr), start (SNP A) and end (SNP B) positions, absolute occurrence probability in the tumor entities (breast, color., gastr., lung, medul., ov., pro., renal), and the total occurrence over all tumor samples (cancer) and in healthy tissue samples (normal), respectively, and the related classification of the BPRs (tumor entity-specific (1)—occurrence is ≥ 1% in exclusively one tumor entity with or without being found in healthy samples, cancer-specific (2)—occurrence is ≥ 1% in more than 25% of the entities and in normal samples < 0.5%, common (3)—occurrence is ≥ 1% in ≥ 25% of the entities and ≥ 0.5% in normal samples.

Abbreviations: color.—colorectal; gastr.—gastric; medul.—pediatric medulloblastoma; ov.—ovarian; pro.—prostate; ren.—renal